A COMPUTATIONALLY EFFICIENT ALGORITHM TO LEVERAGE AVERAGE INFORMATION REML FOR (CO)VARIANCE COMPONENT ESTIMATION IN THE GENOMIC ERA

A computationally efficient algorithm to leverage average information REML for (co)variance component estimation in the genomic era

Abstract Background Methods for estimating variance components (VC) using restricted maximum likelihood (REML) typically require elements from the inverse of the coefficient matrix of the mixed model equations (MME).As genomic information becomes more prevalent, the coefficient matrix of the MME becomes LAUNDRY LIQUID denser, presenting a challenge

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The challenges and opportunities of conducting a clinical trial in a low resource setting: The case of the Cameroon mobile phone SMS (CAMPS) trial, an investigator initiated trial

Abstract Conducting clinical trials in developing countries often presents significant ethical, organisational, cultural and infrastructural challenges to researchers, pharmaceutical companies, sponsors and regulatory bodies.Globally, these regions are under-represented in research, yet this population stands to gain more from research in these set

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High-temperature protective coatings for C/SiC composites

Carbon fiber-reinforced silicon carbide (C/SiC) composites were well-established light weight materials combining high specific strength and damage tolerance.For Athletic Pants high-temperature applications, protective coatings had to provide oxidation and corrosion resistance.The literature data introduced various technologies and materials, which

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The effects of visitors and social isolation from a peer on the behavior of a mixed-species pair of captive gibbons

Abstract Human visitors affect the behavior of captive animals, which is the so-called visitor effect.The number and behavior of visitors may influence stress-related behaviors in captive animals, such as self-scratching, yawning, and visitor-directed vigilance.A social group setting can be applied to alleviate such negative visitor effects and fac

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